Autism Research Trio (ART) in Taiwan ()

Autism spectrum disorder (ASD) is a highly prevalent and complex brain disorder characterized by dysfunctional social interactions, communication difficulties, and repetitive patterns of behaviors/interests. Over the past decade, the prevalence rate of ASD has increased; currently, ASD affects 1 in 45 children and adolescents in the US, and 1 in 100 children in Taiwan. The exact causal mechanism for ASD remains unclear; therefore, there is no effective treatment for ASD. To answer this important question, we teamed up with a psychiatrist (Dr. Susan Shur-Fen Gau), a hiPSC expert (Dr. Dr. Hsiang-Po Huang), experts in human genome (Drs. Shih-Feng Tsai and Shu-Jui Hsu), and a neuroscientist (Dr. Hsien-Sung Huang). Our goal is not only to decode ASD but also to train the best scientists of their generation.
自閉症是一個嚴重的神經發育疾病,其在兒童及青少年中的盛行率為1/45。然而,自閉症的致病機轉,仍尚未清楚。自閉症的致病之謎,堪稱為神經科學領域中,最後一道難解的謎題。也因此,世界上各個先進的國家,無不投入大量的人力與資源,來解開這道世紀之謎。當然,台灣在這場世界級的競技中,亦不能缺席。為了達成這個目標,我們在台灣本土內,結合了自閉症專家(高淑芬醫師)、人類誘導型多潛能幹細胞專家(黃祥博醫師)、人類基因體學專家(蔡世峰醫師和許書睿老師)和神經科學專家(黃憲松老師),來一起解這道難解之謎。我們的目標,除了能夠在自閉症的研究領域中,有重大的發現與突破之外,也希望能夠孕育出台灣下一代傑出的科學家。